Indian Journal of Pathology and Microbiology
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Year : 2010  |  Volume : 53  |  Issue : 4  |  Page : 811-813

Primary epithelioid angiosarcoma of bone: A case report with immunohistochemical study

1 Department of Pathology, Kasturba Medical College, Manipal University, Manipal, India
2 Department of Orthopaedics, Kasturba Medical College, Manipal University, Manipal, India

Correspondence Address:
Ranjini Kudva
Professor, Department of Pathology, Kasturba Medical College, Manipal University, Manipal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.72103

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Primary malignant vascular tumors of the bone are exceedingly rare and represent <1% of primary malignant bone tumors. Angiosarcoma is a malignant mesenchymal neoplasm in which the neoplastic cells demonstrate endothelial differentiation. Epithelioid angiosarcoma (EA) is a rare variant of angiosarcoma that is characterized by large cells with an epithelioid morphology. EA is an aggressive tumor with poor prognosis. Here, we present a case of a 62-year-old man who had primary EA of the left tibia. He was treated with amputation and chemotherapy. After 1 month of chemotherapy, he developed pleural effusion and died.

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