Indian Journal of Pathology and Microbiology
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Year : 2012  |  Volume : 55  |  Issue : 4  |  Page : 506-508

Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient

1 Department of Pathology, Global Hospitals and Health City, Chennai, Tamilnadu, India
2 Department of Gastroenterology and Hepatology, Global Hospitals, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Sushma Patra
Department of Pathology, Global Hospitals and Health City, Chennai-600 100, Tamilnadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.107792

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Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.

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