Indian Journal of Pathology and Microbiology
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Year : 2012  |  Volume : 55  |  Issue : 4  |  Page : 569-571

Cytokeratin-positive primitive neuroectodermal tumor of the prostate: Case report and review of literature

1 Department of Pathology, College of Medicine, Sultan Qaboos University, Sultanate of Oman
2 Department of Medicine, Medical Oncology Unit, Sultan Qaboos University, Sultanate of Oman

Correspondence Address:
Ibrahim Al Haddabi
Sultan Qaboos University. P. O. Box 2572, PC 111 Muscat
Sultanate of Oman
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.107826

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Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) of the prostate is extremely rare. Here, we report a case of ES/PNET of prostate in a 24-year-old man presenting with dysuria and pelvic discomfort. Computed tomography scan revealed a heterogeneous mass involving the prostate without evidence of distant metastases. Histologically, the tumor was composed of small round blue cells strongly and diffusely positive for CD99 and epithelial markers. Fluorescence in situ hybridization confirmed rearrangement of the Ewing's sarcoma region on chromosome 22.

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