Indian Journal of Pathology and Microbiology
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Year : 2013  |  Volume : 56  |  Issue : 1  |  Page : 40-42

Metastatic renal cell carcinoma in the nasopharynx

1 Department of Otorhinolaryngology, Yenikent Government Hospital, Sakarya, Turkey
2 Okmeydani Training and Research Hospital, Istanbul, Turkey
3 Department of Pathology, Okmeydani Training and Research Hospital, Istanbul, Turkey

Correspondence Address:
Yavuz Atar
Cayici Mh. Ayca Sk. no: 15 Osmanli Konaklari villa no: 19, Sapanca, Sakarya
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.116147

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Metastatic renal cell carcinoma of the nasopharynx, nasal cavity, and paranasal sinuses can be misdiagnosed as primary malignant or benign diseases. A 33-year-old male attended our outpatient clinic complaining of difficulty breathing through the nose, bloody nasal discharge, postnasal drop, snoring, and discharge of phlegm. Endoscopic nasopharyngeal examination showed a vascularized nasopharyngeal mass. Under general anesthesia, multiple punch biopsies were taken from the nasopharynx. Pathologically, the tumor cells had clear cytoplasm and were arranged in a trabecular pattern lined by a layer of endothelial cells. After the initial pathological examination, the pathologist requested more information about the patient's clinical status. A careful history revealed that the patient had undergone left a nephrectomy for a kidney mass diagnosed as renal cell carcinoma 3 years earlier. Subsequently, nasopharyngeal metastatic renal cell carcinoma was diagnosed by immunohistochemical staining with CD10 and vimentin. Radiotherapy was recommended for treatment.

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