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LETTER TO EDITOR  
Year : 2014  |  Volume : 57  |  Issue : 1  |  Page : 162-163
Erratum to chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia: Accelerated phase: A rare case with review of literature, published in Indian J Pathol Microbiol. Jul-Sep; 56(3):303-5


1 Department of Hematology, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, India
2 Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, India

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Date of Web Publication17-Apr-2014
 

How to cite this article:
Kumar N, Ahluwalia J, Malhotra P, Sachdeva MS. Erratum to chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia: Accelerated phase: A rare case with review of literature, published in Indian J Pathol Microbiol. Jul-Sep; 56(3):303-5. Indian J Pathol Microbiol 2014;57:162-3

How to cite this URL:
Kumar N, Ahluwalia J, Malhotra P, Sachdeva MS. Erratum to chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia: Accelerated phase: A rare case with review of literature, published in Indian J Pathol Microbiol. Jul-Sep; 56(3):303-5. Indian J Pathol Microbiol [serial online] 2014 [cited 2021 Sep 21];57:162-3. Available from: https://www.ijpmonline.org/text.asp?2014/57/1/162/130943


Sir,

This is in reference to the query put forward on the case report entitled "Chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia (CML) - Accelerated phase: A rare case with review of literature," published in Jul-Sep;56(3):303-5 of Indian J Pathol Microbiol.

The reader has observed some errors in the karyogram image provided in the article (Jul-Sep;56(3):303-5 Indian J Pathol Microbiol)and points out queries regarding same. We appreciate the observations made by the observer. The karyogram does not belong to the index case and has been inadvertently uploaded. We sincerely apologize for this error and for any inconvenience caused. In view of query by the observer regarding the presence of t(9;22) in this patient, we would like to provide image of molecular work-up, i.e., reverse transcriptase polymerase chain reaction for BCR-ABL fusion transcript [Figure 1]. This photograph of gel confirms the presence of BCR-ABL fusion transcript of b3a2 type in the patient at the time of initial bone marrow examination.
Figure 1: Multiplex polymerase chain reaction for BCR-ABL. b3a2 transcript was detected in the index patient (lane 3)

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In response to the third query, CD20 and CD5 immunostain has been performed on bone marrow trephine biopsy done at the time of diagnosis of CML. The stain reveals the presence of four small interstitial aggregates of CD20 positive cells. These cells are also positive for CD5. However, the differential leukocyte count on peripheral blood and bone marrow smears showed only 3% lymphocytes.

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Correspondence Address:
Narender Kumar
Department of Hematology, Level 5, Research Block A, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.130943

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