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Indian Journal of Pathology and Microbiology
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CASE REPORT
Year : 2014  |  Volume : 57  |  Issue : 4  |  Page : 611-613

Adenoid cystic carcinoma of the breast: Report of two cases with immunohistochemical profile of C-kit and MYB overexpression


1 Department of Pathology, Soonchunhyang University College of Medicine, Bucheon, Korea
2 Department of Surgery, Soonchunhyang University College of Medicine, Bucheon, Korea

Correspondence Address:
Susie Chin
Department of Pathology, Soonchunhyang University College of Medicine, 170 Jomaru-ro, Wonmi-gu, Bucheon 420-767
Korea
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.142693

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Adenoid cystic carcinoma (ACC) is a rare tumor with characteristic histologic features. Staining with basal markers for estrogen receptor, progesterone receptor, and HER2 usually shows negative results. Immunohistochemical analysis of C-kit and MYB overexpression of the ACC also has been reported. We report two cases of ACC of the breast with C-kit and MYB overexpression that clinically confirm these previously reported characteristics and suggest that further molecular study of the expression of these two proteins can lead to future therapeutic strategies.


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