Indian Journal of Pathology and Microbiology
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Year : 2015  |  Volume : 58  |  Issue : 2  |  Page : 226-228

Angiomyomatous hamartoma in an inguinal lymph node with proliferating pericytes/smooth muscle cells, plexiform vessel tangles, and ectopic calcification

1 Department of Pathology, Taipei Medical University, Taipei, Taiwan
2 Department of Surgery, Division of General Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
3 Department of Radiology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan

Correspondence Address:
Dr. Chii-Hong Lee
Department of Pathology, Shuang Ho Hospital, Taipei Medical University, 291, Zhongzheng Road, Zhonghe District, New Taipei City 23561
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.155325

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Angiomyomatous hamartoma (AMH) is a rare benign lesion, which occurs almost exclusively in the inguinal lymph nodes. We herein report a case of a female elder who presented with a long-standing inguinal mass. Microscopically, the mass showed a zonal distribution, characterized by thick-walled muscular vessels, fibrosis, and calcification in the hilum and proliferating spindle cells around thin-walled vessels and plexiform vessel tangles at the periphery. The spindle cells show positive immunoreactivity of smooth muscle actin and CD34 with a heterogeneous expression of desmin and CD44. Although the pathogenesis of AMH remains uncertain, the histological features and immunohistochemical findings of this case imply a disordered or exuberant angiogenic process.

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