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| Year : 2015 | Volume
: 58
| Issue : 2 | Page : 267 |
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| Quiz Answer page |
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KP Aravindan
Department of Pathology, Government of Medical College, Kozhikode, Kerala, India
Click here for correspondence address and email
| Date of Web Publication | 17-Apr-2015 |
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How to cite this article:
Aravindan K P. Quiz Answer page. Indian J Pathol Microbiol 2015;58:267 |
Quiz 3/2015
Chediak Higashi syndrome in accelerated phase
In the first picture, typical myeloid inclusions of Chediak-Higashi syndrome are seen (orange arrow). The dark arrows point to hemophagocytic cells. Second picture shows many dot like single inclusions in the lymphocytes and macrophages (red arrows). A myeloid cell also shows the typical inclusions (dark arrow). The lesions shown are typical inclusions of the disease and hemophagocytosis, which signifies an accelerated phase of the disease. [1],[2]
Quiz 4/2015
Papillary carcinoma thyroid, Cribriform-Morular variant. Morules stained with CD-10.
In the first picture (hematoxylin and eosin) a papillary tumor with solid areas is seen. A tiny bit of colloid indicating thyroid origin can be seen. The nuclei of the papillary tumor in oval and some are clear. The solid areas contain rounded morules of squamoid cells. [3] These morules stain intensely with CD-10. Tubular (cribriform) areas can also be seen in the second picture. [4] The patient is being investigated for Familial adenomatous polyposis.
 References | |  |
| 1. | Patne SC, Kumar S, Bagri NK, Kumar A, Shukla J. Chédiak-higashi syndrome : A case report. Indian J Hematol Blood Transfus 2013;29:80-3.  |
| 2. | Pullarkat ST. Accelerated phase of Chediak-Higashi syndrome. Blood 2012;119:5. |
| 3. | Ito Y, Miyauchi A, Ishikawa H, Hirokawa M, Kudo T, Tomoda C, et al. Our experience of treatment of cribriform morular variant of papillary thyroid carcinoma; difference in clinicopathological features of FAP-associated and sporadic patients. Endocr J 2011;58:685-9. |
| 4. | Cameselle-Teijeiro J, Menasce LP, Yap BK, Colaco RJ, Castro P, Celestino R, et al. Cribriform-morular variant of papillary thyroid carcinoma : m0 olecular characterization of a case with neuroendocrine differentiation and aggressive behavior. Am J Clin Pathol 2009;131:134-42. |
Correspondence Address:
Dr. K P Aravindan
Department of Pathology, Government of Medical College, Kozhikode, Kerala
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0377-4929.155369
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