Indian Journal of Pathology and Microbiology
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  Table of Contents    
Year : 2015  |  Volume : 58  |  Issue : 2  |  Page : 267
Quiz Answer page

Department of Pathology, Government of Medical College, Kozhikode, Kerala, India

Click here for correspondence address and email

Date of Web Publication17-Apr-2015

How to cite this article:
Aravindan K P. Quiz Answer page. Indian J Pathol Microbiol 2015;58:267

How to cite this URL:
Aravindan K P. Quiz Answer page. Indian J Pathol Microbiol [serial online] 2015 [cited 2023 Oct 2];58:267. Available from:

Quiz 3/2015

Chediak Higashi syndrome in accelerated phase

In the first picture, typical myeloid inclusions of Chediak-Higashi syndrome are seen (orange arrow). The dark arrows point to hemophagocytic cells. Second picture shows many dot like single inclusions in the lymphocytes and macrophages (red arrows). A myeloid cell also shows the typical inclusions (dark arrow). The lesions shown are typical inclusions of the disease and hemophagocytosis, which signifies an accelerated phase of the disease. [1],[2]

Quiz 4/2015

Papillary carcinoma thyroid, Cribriform-Morular variant. Morules stained with CD-10.

In the first picture (hematoxylin and eosin) a papillary tumor with solid areas is seen. A tiny bit of colloid indicating thyroid origin can be seen. The nuclei of the papillary tumor in oval and some are clear. The solid areas contain rounded morules of squamoid cells. [3] These morules stain intensely with CD-10. Tubular (cribriform) areas can also be seen in the second picture. [4] The patient is being investigated for Familial adenomatous polyposis.

   References Top

Patne SC, Kumar S, Bagri NK, Kumar A, Shukla J. Chédiak-higashi syndrome : A case report. Indian J Hematol Blood Transfus 2013;29:80-3.  Back to cited text no. 1
Pullarkat ST. Accelerated phase of Chediak-Higashi syndrome. Blood 2012;119:5.  Back to cited text no. 2
Ito Y, Miyauchi A, Ishikawa H, Hirokawa M, Kudo T, Tomoda C, et al. Our experience of treatment of cribriform morular variant of papillary thyroid carcinoma; difference in clinicopathological features of FAP-associated and sporadic patients. Endocr J 2011;58:685-9.  Back to cited text no. 3
Cameselle-Teijeiro J, Menasce LP, Yap BK, Colaco RJ, Castro P, Celestino R, et al. Cribriform-morular variant of papillary thyroid carcinoma : m0 olecular characterization of a case with neuroendocrine differentiation and aggressive behavior. Am J Clin Pathol 2009;131:134-42.  Back to cited text no. 4

Correspondence Address:
Dr. K P Aravindan
Department of Pathology, Government of Medical College, Kozhikode, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.155369

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