Indian Journal of Pathology and Microbiology
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Year : 2015  |  Volume : 58  |  Issue : 4  |  Page : 448-452

Cytologic diagnosis of gastric submucosal lesions by endoscopic ultrasound-guided fine-needle aspiration: A single center experience in Saudi Arabia

1 Division of Pathology, King Khalid University Hospital, King Saud University, Riyadh; Division of Pathology, Alfaisal University, Riyadh, Saudi Arabia
2 Division of Gastroenterology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia; Division of Gastroenterology, The McGill University Health Center, Montreal General Hospital, McGill University, Montreal, Canada
3 Division of Gastroenterology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia
4 Division of Surgery, King Khalid University Hospital, Riyadh, Saudi Arabia

Correspondence Address:
Dr. Emad Raddaoui
Division of Pathology, King Khalid University Hospital, College of Medicine, King Saud University, P.O. Box 2925/32, Riyadh 11461
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.168868

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Background and Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) sampling has become standard practice for the diagnosis of submucosal gastrointestinal (GI) lesions. The aim of this study was to determine the utility of EUS-guided FNA cytology in the diagnosis of deeply seated gastric mass lesions. Materials and Methods: Thirteen patients with deeply seated gastric mass lesions were diagnosed by EUS-FNA. Adequate cytology material was present in all cases. Cell blocks were available in 10 cases. Surgical resections were performed in 8 cases. Immunohistochemical (IHC) studies were done on cell blocks in 9 cases and on 6 resected specimens. Seven cases has proved to be GI stromal tumors (GIST), in four of them, cell blocks were available, and resection for GIST was performed in 5 cases. IHC stains that were performed in cytology, as well as resection specimens, revealed similar results in each patient. Conclusion: EUS-FNA cytology, when combined with a histologic assessment of cell blocks provides accurate and efficient tissue diagnosis of a wide variety of deeply seated gastric mass lesions.

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