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Indian Journal of Pathology and Microbiology
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CASE REPORT
Year : 2016  |  Volume : 59  |  Issue : 1  |  Page : 110-112

Severe anemia due to parvovirus B19 in a silver haired boy


1 Department of Pediatrics, King George's Medical University, Lucknow, Uttar Pradesh, India
2 Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India

Correspondence Address:
Nishant Verma
502/B, Halwasiya Lorepur Residency, New Hyderabad, Lucknow - 226 007, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.178228

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Griscelli syndrome (GS) is a rare autosomal recessive immunodeficiency disorder in which the affected children present with characteristic silvery-white hairs. The hair microscopy of these children is characteristic and is helpful in differentiating GS from Chediak-Higashi syndrome which also presents with immunodeficiency and silver hairs. We report a 17-month-old boy with GS type 2 who presented with severe anemia. Bone marrow examination of the child suggested parvovirus B19 as the cause of severe anemia, which was later confirmed by DNA polymerase chain reaction.


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