Primary signet cell adenocarcinoma of bladder

Prateek Kinra; SP Rashmi; Aftab Alam; Harkirat Singh; SC Dash

doi:10.4103/IJPM.IJPM_201_16

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CASE REPORT

Year : 2017 | Volume : 60 | Issue : 4 | Page : 584-586

Primary signet cell adenocarcinoma of bladder

Prateek Kinra¹, SP Rashmi¹, Aftab Alam², Harkirat Singh³, SC Dash⁴
¹ Department of Pathology, Command Hospital Air Force, Bengaluru, Karnataka, India
² Department of Radiology, Command Hospital Air Force, Bengaluru, Karnataka, India
³ Department of Nuclear Medicine, Command Hospital Air Force, Bengaluru, Karnataka, India
⁴ Department of Urology, Command Hospital Air Force, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Prateek Kinra
Department of Pathology, Command Hospital Air Force, Old Airport Road, Bengaluru - 560 007, Karnataka
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/IJPM.IJPM_201_16

Primary signet cell cancer of the urinary bladder is a relatively rare entity. Since there is no mucinous epithelium in the bladder, It is proposed that the tumor arises from metaplastic urothelium. Two thirds of the tumours are mucin secreting, in most of which the site of the deposition is either extracellular or intracellular displacing the nucleus to a peripheral crescent, giving the cells a signet ring appearance. The tumours are most often infiltrative and diffusely involving the majority of the bladder akin to its name sake in stomach. It is essential to distinguish this carcinoma from gastrointestinal metastases as different therapeutic strategies are often necessary.

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