Indian Journal of Pathology and Microbiology
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Year : 2018  |  Volume : 61  |  Issue : 1  |  Page : 109-112

Strongyloides stercoralis hyperinfection in an unconscious diabetic patient with dermatomyositis

1 Department of Medical Parasitology and Mycology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
2 Emergency Department of Emam Reza Hospital, Qom Medical Center, Social Security Organization, Qom, Iran
3 Department of Medical Parasitology and Mycology, Amol Faculty of Paramedics, Mazandaran University of Medical Sciences, Sari, Iran
4 Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Eshrat Beigom Kia
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, P. O. Box: 14155-6446, Tehran
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPM.IJPM_734_16

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A case of Strongyloides stercoralis hyperinfection in a patient with dermatomyositis and diabetes mellitus is herein reported. The case was a 60-year-old female admitted due to watery diarrhea and unconsciousness. She had a 10-year history of chronic immunosuppressive therapy including methotrexate and prednisolone for dermatomyositis. Stool parasitological examination revealed numerous rhabditiform larvae of threadworm “S. stercoralis.” Larva in stool sample was characterized by sequencing of mitochondrial DNA. After treatment with ivermectin, the patient recovered without evidence of S. stercoralis in follow-up stool samples. In endemic areas, stool examination for detection of S. stercoralis should be performed on a regular basis for all patients receiving immunosuppressive therapy, as early detection and treatment are necessary to minimize complications of severe strongyloidiasis.

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