Indian Journal of Pathology and Microbiology
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Year : 2018  |  Volume : 61  |  Issue : 1  |  Page : 94-97

Sporadic lymphangioleiomyomatosis with multiple atypical features: A case report and literature review

1 Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
2 Department of Oncology, The First Affiliated Hospital of Lanzhou University, Lanzhou, Gansu, China

Correspondence Address:
Maohui Feng
Department of Oncology, Zhongnan Hospital of Wuhan University, No 169, Donghu Road, Wuchang District, Wuhan 430071
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPM.IJPM_843_16

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Lymphangioleiomyomatosis (LAM) is a rare, genetically determined, progressive interstitial lung disease, which almost exclusively affects women, especially at the childbearing age. The initial symptoms and radiographic changes in a patient with LAM are always associated with the respiratory system. Here, we present a case of mediastinal and abdominal LAM of a 22-year-old male, where LAM cells are negative for human melanoma black-45 ( HMB-45). The report of this uncharacterized LAM case will make a significant contribution to the realization of LAM associated clinical features, diagnostic approaches, and its afterward treatments.

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