|
|
| Year : 2018 | Volume
: 61
| Issue : 2 | Page : 169 |
|
| From the Editor's Desk |
|
|
Ranjan Agrawal
MD; FICPath; MIAC, DHA Professor, Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh, India
Click here for correspondence address and email
| Date of Web Publication | 20-Apr-2018 |
|
|
 |
|
How to cite this article:
Agrawal R. From the Editor's Desk. Indian J Pathol Microbiol 2018;61:169 |
After an initial delay of the January issue, we are back into the flow with the April issue. It has been six decades since the start of Indian Journal of Pathology and Microbiology (IJPM). I would like to reinstate that the high scientific standards of the articles would be maintained.
The technical simplicity, easy availability, and comparatively lower cost enhance the role of p53 as a biomarker in risk stratification for patients with Barrett's esophagus. This has very well been mentioned by Krothapalli et al. in their article published in this issue.[1]
Lymphangiogenesis correlates with a poor prognosis in invasive ductal carcinoma (IDC) breast. D240 antibody, a specific marker for lymphatic endothelium, differentiates lymphatic from vascular endothelium. Guleria et al. in their article emphasized that LI and lymphangiogenesis, as opposed to blood vessel invasion, are better prognostic indicators in IDC breast.[2]
The manuscript by Sterlacci et al. recommends additional MUC5AC staining for thyroid transcription factor 1negative adenocarcinoma in the lung for the differentiation of a possible metastasis in the presence of pancreatic ductal adenocarcinoma.[3]
There has been a shift from the morphological and clinical classification to a more evolved molecular classification. This usually incorporates mutations in Janus kinase 2 (JAK2), MPL, and calreticulin (CALR) genes which carry not only diagnostic but also prognostic relevance. Rabade et al. have highlighted these features in an illustrative and descriptive manner.[4]
Urothelial carcinoma (UC) is one of the most frequent epithelial tumors worldwide. Turk et al. in their study investigated the protein expressions of caspase-8, p53, murine double minute 2 (mdm2), and p14ARF in nonmuscle UCs and correlated the findings with the clinical and pathological findings. They further observed that the staining pattern of caspase-8 may help in determining the stage in nonmuscle UC, whereas the expression of p53 and mdm2 relates to recurrence.[5]
Garg et al. in their article on core needle biopsies from four major organs, namely breast, prostate, soft tissue, and lymph nodes having surgical disorders emphasized the current practices of handling and reporting of core needle biopsies, mentioning their importance.[6] The article by Goyal et al. signifies the occurrence of various qualitative defects in patients with normal sperm counts, which were referred for baseline investigation.[7]
I am sure that more and more members would contribute their valuable research work to IJPM and also cite articles published in IJPM in all their submissions.
Jai Hind
 References | |  |
| 1. | Krothapalli M, Kini JR, Kini H, Sahu KK, Shenoy S, Krishna SG, et al. Evaluation of p53 protein expression in Barrett esophagus. Indian J Pathol Microbiol 2018;61:170-5.  [Full text] |
| 2. | Guleria P, Srinivas V, Basannar D, Dutta V. Comparison of lymphangiogenesis, lymphatic invasion, an axillary lymph node metastasis in breast carcinoma. Indian J Pathol Microbiol 2018;61:176-80. [Full text] |
| 3. | Sterlacci W, Fieg IM, Veits L, Tzankov A. Diagnostic and prognostic impact of mucin 1-6 expression in non-small cell lung cancer. Indian J Pathol Microbiol 2018;61:187-91. [Full text] |
| 4. | Rabade N, Subramanian PG, Kodgule R, Raval G, Joshi S, Chaudhary S, et al. Molecular genetics of BCR? ABL 1 negative myeloproliferative neoplasma in India. Indian J Pathol Microbiol 2018;61:209-13. [Full text] |
| 5. | Turk NS, Eskicorapci S, Aybek Z, Tuncay L. The determination of stage in non muscle urothelial carcinoma: Staining pattern of Caspase8. Indian J Pathol Microbiol 2018;61:192-6. |
| 6. | Garg P, Pathak P, Goyal R, Arora VK, Singh N. Current practice in handling and reporting needle biopsies: A hospital based survey. Indian J Pathol Microbiol 2018;61:197-200. [Full text] |
| 7. | Goyal R, Kotru M, Gogia A, Sharma S. Qualitative defects with normal sperm counts in a patient attending infertility clinic. Indian J Pathol Microbiol 2018;61:233-5. [Full text] |
Correspondence Address:
Ranjan Agrawal
MD; FICPath; MIAC, DHA Professor, Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0377-4929.230586
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Article Access Statistics | | | Viewed | 2334 | | | Printed | 71 | | | Emailed | 0 | | | PDF Downloaded | 112 | | | Comments | [Add] | | |
|
|
