Indian Journal of Pathology and Microbiology
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Year : 2019  |  Volume : 62  |  Issue : 2  |  Page : 287-289

A unique case of eyelid metastasis from chondroid chordoma

Department of Pathology, The First Affiliated Hospital of Zhengzhou University; Department of Pathology, Basic Medicine College of Zhengzhou University, Zhengzhou, China

Correspondence Address:
Huixiang Li
Department of Pathology, First Affiliated Hospital and College of Basic Medical Sciences, Zhengzhou University, Jianshe Road, Erqi Ward, Zhengzhou, 450052
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPM.IJPM_387_18

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A unique case of eyelid metastasis from nasopharyngeal chondroid chordoma in a 63-year-old woman was reported. Chordomas are rare tumors of the bone deriving from remnants of the embryonic notochord. Histologically, the tumor showed lobulated structure and concludes two types of cells: liquid drop cell and small round/cubic cell. Immunohistochemically, AE1/AE3, epithelial membrane antigene (EMA), and S100 showed a uniform and strong positivity. It has a great capacity for recurrence and malignant transformation, despite their slow-growing nature. The most common sites of metastases are liver, lungs, and bones. The eyelid metastasis from chordoma is an extremely rare finding, which may suggest a poor prognosis for the patient. Its significant clinicopathological characteristic could prompt us to take it into consideration when assessing the patient's prognosis.

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