Indian Journal of Pathology and Microbiology
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Year : 2019  |  Volume : 62  |  Issue : 3  |  Page : 470-472

A rare case of primary cutaneous diffuse large B-cell lymphoma, leg type in a patient with chronic lymphedema of the leg

1 Department of Pathology, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, India
2 Institute of Applied Dermatology, Kasargod, Kerala, India
3 Mediclu Diagnostics, Bengaluru, Karnataka, India

Correspondence Address:
Basavaraj Vijaya
Department of Pathology, JSS Medical College, Shivarathreeshwar Nagar, Mysuru - 570 015, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPM.IJPM_581_18

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A rare complication of chronic lymphedema is development of cutaneous malignant tumors particularly cutaneous lymphomas. We report a case of primary cutaneous diffuse large B-cell lymphoma, leg type, associated with chronic lymphedema of the lower limbs. A literature review identified 12 additional cases of primary cutaneous lymphomas associated with chronic lymphedema. Chronic lymphatic stasis may cause a local dysfunction of the immune system that predisposes to the induction of neoplasia, cutaneous lymphomas in particular.

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