Indian Journal of Pathology and Microbiology
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Year : 2020  |  Volume : 63  |  Issue : 2  |  Page : 267-269

Myxoid meningioma: A case report of an extremely rare subtype of metaplastic meningioma

1 Department of Pathology, PGIMER and Dr. RML Hospital, New Delhi, India
2 Department of Neurosurgery, PGIMER and Dr. RML Hospital, New Delhi, India

Correspondence Address:
Arvind Ahuja
Department of Pathology, Room No. 323, PGIMER and Dr. RML Hospital, New Delhi - 110 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPM.IJPM_111_19

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Myxoid meningioma is a rare histological variant of meningiomas grouped into the subtype of metaplastic meningiomas (World Health Organization grade I) characterized by the presence of myxoid areas and meningothelial cells along with unique ultrastructural features that help distinguish it from other meningiomas. Hereby, we report a case of a myxoid meningioma in a 40-year-old female who presented with altered sensorium and loss of consciousness. Imaging studies showed a dura-based solitary mass located in the left frontal lobe. The tumor was excised completely. Histopathology revealed a benign appearing myxoid neoplasm with uniform elongated cells, without any atypia and a very low mitotic activity. Immunohistochemical stains showed positivity for vimentin and epithelial membrane antigen confirming the diagnosis of myxoid meningioma. Only seven cases of myxoid meningioma have been reported till date in the literature and ours is the eighth case.

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