Indian Journal of Pathology and Microbiology
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Year : 2020  |  Volume : 63  |  Issue : 4  |  Page : 615-617

Anaplastic Lymphoma Kinase positive large B cell lymphoma of ileocaecal mesentery: A case report

Department of Pathology, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu, India

Correspondence Address:
Divya Gnanasekaran
Department of Pathology, GEM Hospital and Research Centre, Coimbatore, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPM.IJPM_296_19

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ALK+ large B cell lymphoma (LBCL) is a very rare aggressive neoplasm. It accounts for less than 1% of diffuse large B cell lymphoma (DLBCL). This is a case report of ALK+ DLBCL in a 34-year-old woman with an ileocaecal mesenteric mass. Microscopically, the neoplastic cells were of high grade along with a spindle cell component. Immunohistochemistry revealed ALK+, MUM-1+, LCA+, Vimentin+, EMA+ and negative for CK 20, CK 7, neuroendocrine, melanocytic, muscle specific, and GIST panel markers. This case report, hence, presents the rarity of this tumor.

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