Indian Journal of Pathology and Microbiology
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Year : 2021  |  Volume : 64  |  Issue : 1  |  Page : 180-182

Endocrine mucin-producing sweat gland carcinoma of the peno-scrotum with systemic metastases: A rare case report

1 Consultant Histopathologist, Yashoda Hospitals, Secunderabad, Telangana, India
2 Department of Pathology, Yashoda Hospitals, Secunderabad, Telangana, India
3 Consultant Radiation Oncologist, Yashoda Hospitals, Secunderabad, Telangana, India
4 Consultant Pathologist, Yashoda Hospitals, Secunderabad, Telangana, India

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Ambreen Aman
No 10, 1st Cross, Mudamma Garden, Benson Town, Jayamahal Extension, Bangalore - 560 046, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/IJPM.IJPM_342_19

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Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare adnexal tumor with a predilection for the skin of the eyelid. It has also been reported in other areas of the face. Extra facial location has rarely been reported. They are twice as common in the females as compared to men and frequently affect the elderly between 50 and 80 years of age. It is a low-grade carcinoma with no reported cases of metastases, although a few cases with recurrences have been reported. Since it was first described by Flieder et al. in 1997, fewer than 60 cases have been reported in the literature. We describe one such case of EMPSGC in an adult male occurring at an unusual location, the peno-scrotal junction with systemic metastases to bilateral inguinal and iliac lymph nodes, multiple bones, and pancreas. Unlike previously reported cases, our patient worsened rapidly and succumbed to the disease six months after initiation of chemotherapy and radiotherapy. To the best of our knowledge, this is the first reported case of its kind in modern published literature.

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