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Indian Journal of Pathology and Microbiology
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CASE REPORT
Year : 2021  |  Volume : 64  |  Issue : 5  |  Page : 143-145

Epithelioid hemangioma of liver—The first reported case


1 Department of Surgery, Moritz Kaposi General Hospital, Kaposvár, 20-32. Tallián Gy. Street, Kaposvár 7400; Doctoral School of Clinical Medicine of University of Debrecen, Debrecen, 1. Egyetem Square, Debrecen 4032, Hungary
2 Department of Surgery, Moritz Kaposi General Hospital, Kaposvár, 20-32. Tallián Gy. Street, Kaposvár 7400, Hungary
3 Department of Pathology, Moritz Kaposi General Hospital, Kaposvár, 20-32. Tallián Gy. Street, Kaposvár 7400, Hungary
4 Department of Surgery, Borsod-Abaúj-Zemplén County Hospital and University Teaching Hospital, Miskolc, 72-76. Szentpéteri Gate, Miskolc 3526, Hungary

Correspondence Address:
Adrienn Biro
Department of Surgery, Moritz Kaposi General Hospital, Kaposvár, 20-32 Tallián Gy. Street, Kaposvár 7400
Hungary
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJPM.IJPM_148_20

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Epithelioid hemangioma, otherwise known as angiolymphoid hyperplasia with eosinophilia, is a rare benign vasoproliferative disease with an unknown etiology. We report the case of a 42-year-old man with routine bloods test showing mildly elevated serum bilirubin level. CT scan revealed a lesion in the left liver lobe not typical of FNH. PET/CT scan and a dynamic liver MRI were consistent with a malignant mass. Surgical resection was performed. Histopathology of the 45 mm mass reported well-defined, slightly lobular proliferations of capillary-sized vessels around several central muscular vessels. Although the endothelial cells revealed a “hobnail” appearance, none of them showed pleomorphism or mitotic activity. Endothelial cells showed reactivity for the endothelial markers (CD34, CD31) and smooth muscle was detected in the blood vessel walls via immunohistochemistry. Despite its benign nature, epithelioid hemangioma of the liver can lead to a diagnostic and therapeutic dilemma due to the malignant looking features on imaging modalities.


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