Indian Journal of Pathology and Microbiology


Year
: 2000  |  Volume : 43  |  Issue : 3  |  Page : 325--9

Serum lactate dehydrogenase in diagnosis of megaloblastic anaemia.


T S Jaswal, H C Mehta, V Gupta, M Singh, S Singh 
 Department of Pathology, Medicine and Biochemistry, Pt. BD Sharma PGIMS, Rohtak, Haryana

Correspondence Address:
T S Jaswal
Department of Pathology, Medicine and Biochemistry, Pt. BD Sharma PGIMS, Rohtak, Haryana

The present study was carried out in 75 patients of macrocytic anaemia categorised on bone marrow examination (into megaloblastic and non-megaloblastic anaemia) to evaluate the efficacy of total serum LDH levels and LDH isoenzyme pattern in the diagnosis of megaloblastic anaemia. 25 healthy adults were taken as controls. From this study it can be concluded that total serum LDH levels more than 3000 IU/L are diagnostic of megaloblastic anaemia. Reversed LDH isoenzyme pattern (LDH1 > LDH2) by chloroform inhibition test is an adjuvant in the diagnosis where total serum LDH levels are between 451-3000 IU/L and it will also differentiate megaloblastic anaemia from haemolytic anaemia.


How to cite this article:
Jaswal T, Mehta H, Gupta V, Singh M, Singh S. Serum lactate dehydrogenase in diagnosis of megaloblastic anaemia. Indian J Pathol Microbiol 2000;43:325-9


How to cite this URL:
Jaswal T, Mehta H, Gupta V, Singh M, Singh S. Serum lactate dehydrogenase in diagnosis of megaloblastic anaemia. Indian J Pathol Microbiol [serial online] 2000 [cited 2021 Jan 19 ];43:325-9
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2000;volume=43;issue=3;spage=325;epage=9;aulast=Jaswal;type=0