Indian Journal of Pathology and Microbiology


Year
: 2000  |  Volume : 43  |  Issue : 3  |  Page : 337--41

Leptospirosis in the causation of hepato-renal syndrome in and around Pune.


A Sharma, S A Joshi, S K Srivastave, R Bharadwaj, P M Kahre 
 Department of Microbiology, NDMVP Medical College, Nasik

Correspondence Address:
A Sharma
Department of Microbiology, NDMVP Medical College, Nasik

Fifty cases of hepato-renal dysfunction of unknown etiology were studied over a two-year period. Urine samples were examined microscopically and cultured for Leptospira. Serum samples were examined for antibodies against Leptospira by the Macroscopic slide agglutination test (MSAT). Seventeen out of fifty patients (34%) showed evidence of Leptospiral infection by at least two diagnostic techniques used. 15/17 i.e. 88.2% were positive by dark ground microscopy, 7/17 were diagnosed by culture technique and 16/17 i.e. 94% were confirmed by serology. There was a good correlation between Microscopic agglutination test (MAT) and MSAT. Thus Leptospires seem to play a major role in the causation of hepato-renal dysfunction in and around Pune, Maharashtra.


How to cite this article:
Sharma A, Joshi S, Srivastave S, Bharadwaj R, Kahre P. Leptospirosis in the causation of hepato-renal syndrome in and around Pune. Indian J Pathol Microbiol 2000;43:337-41


How to cite this URL:
Sharma A, Joshi S, Srivastave S, Bharadwaj R, Kahre P. Leptospirosis in the causation of hepato-renal syndrome in and around Pune. Indian J Pathol Microbiol [serial online] 2000 [cited 2021 Jan 19 ];43:337-41
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2000;volume=43;issue=3;spage=337;epage=41;aulast=Sharma;type=0