Indian Journal of Pathology and Microbiology


Year
: 2001  |  Volume : 44  |  Issue : 3  |  Page : 365--6

Clinicohaematological profile of two cases of inhibitors to factor VIII.


A M Shanthala Devi, A Srikrishna, S Sitalaksmi, P Damodar 
 Department of Pathology, Academy of Health Sciences, Banglore

Correspondence Address:
A M Shanthala Devi
Department of Pathology, Academy of Health Sciences, Banglore

Bleeding is a common manifestation of inherited and acquired disorders of haemostasis. Acquired disorders of haemostasis can be of varied etiology like liver disease, DIC, haemorrhagic disease of newborn and inhibitors to coagulation factors. Inhibitors to coagulation factors are an unusual cause of bleeding which can be superimposed on inherited factor deficiencies or sometimes resembles them. The clinical and haematological profile to two cases of factor VIII inhibitors are being presented here, one of which was a known haemophiliac receiving factor VIII therapy and another was a elderly lady with no other apparent underlying disorder. Hence any case of factor VIII deficiency who becomes refractory to factor VIII replacement therapy or those who are detected to have factor deficiency late in life should be investigated for inhibitors.


How to cite this article:
Shanthala Devi A, Srikrishna A, Sitalaksmi S, Damodar P. Clinicohaematological profile of two cases of inhibitors to factor VIII. Indian J Pathol Microbiol 2001;44:365-6


How to cite this URL:
Shanthala Devi A, Srikrishna A, Sitalaksmi S, Damodar P. Clinicohaematological profile of two cases of inhibitors to factor VIII. Indian J Pathol Microbiol [serial online] 2001 [cited 2021 Oct 19 ];44:365-6
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2001;volume=44;issue=3;spage=365;epage=6;aulast=Shanthala;type=0