Indian Journal of Pathology and Microbiology


Year
: 2007  |  Volume : 50  |  Issue : 1  |  Page : 6--10

Clinico-pathological profile of 22 cases of cystic renal dysplasia.


S Singh, R Gupta, S Nigam, N Khurana, Satish Kumar Aggarwal, K Uma Chaturvedi, Ashish Kumar Mandal 
 Department of Pathology, Maulana Azad Medical College, New Delhi

Correspondence Address:
S Singh
Department of Pathology, Maulana Azad Medical College, New Delhi

Renal dysplasia is one of the major renal developmental anomaly characterized by abnormal structural organization and development of metanephric elements. It is usually detected antenatally or in early childhood. The kidney may be multicystic, aplastic, hypoplastic or duplex. We studied 22 cases of cystic renal dysplasia diagnosed over a period often years to identify the spectrum of morphological changes in dysplastic kidney, with special emphasis on mesenchymal changes. Clinical, radiological and gross morphologicalfeatures were noted. Microscopic features were studied in detail, including the epithelial and mesenchymal changes. Twenty-one of the 22 cases studied were children. One case was a 21-year-old adult, which is a rare age at presentation. Male to female ratio was 1.1:1. One of our patients had contra-lateral ureteric stenosis, a rare anomaly reported with renal dysplasia. Ten patients, all autopsy cases, had multi-system congenital anomalies. As cystic renal dysplasia is not a hereditary disease, it must be differentiated from polycystic kidney disease. Other differential diagnoses are cystic nephroma and cystic partially differentiated nephroblastoma. Histopathological examination is the final diagnostic tool since radiological features alone may not be sufficient to exclude other cystic renal lesions. Cartilage may not be seen in all cases of renal dysplasia. Once diagnosed, other associated anomalies should also be looked for.


How to cite this article:
Singh S, Gupta R, Nigam S, Khurana N, Aggarwal SK, Chaturvedi K U, Mandal AK. Clinico-pathological profile of 22 cases of cystic renal dysplasia. Indian J Pathol Microbiol 2007;50:6-10


How to cite this URL:
Singh S, Gupta R, Nigam S, Khurana N, Aggarwal SK, Chaturvedi K U, Mandal AK. Clinico-pathological profile of 22 cases of cystic renal dysplasia. Indian J Pathol Microbiol [serial online] 2007 [cited 2021 Jun 19 ];50:6-10
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2007;volume=50;issue=1;spage=6;epage=10;aulast=Singh;type=0