Indian Journal of Pathology and Microbiology

ORIGINAL ARTICLE
Year
: 2008  |  Volume : 51  |  Issue : 3  |  Page : 367--369

Prevalence of extended spectrum beta lactamase and AmpC beta lactamase producers among Escherichia coli isolates in a tertiary care hospital in Jaipur


Parul Sinha1, Rajni Sharma1, Suman Rishi1, Raman Sharma2, Smita Sood1, Deepali Pathak3 
1 Department of Microbiology and Immunology, Sawai Man Singh Medical College, Jaipur, Rajasthan, India
2 Department of Medicine, Sawai Man Singh Medical College, Jaipur, Rajasthan, India
3 Department of Forensic Medicine, Sawai Man Singh Medical College, Jaipur, Rajasthan, India

Correspondence Address:
Rajni Sharma
P-3, Tilak Marg, C- Scheme, Jaipur, Rajasthan
India

Resistance to broad spectrum β lactams, mediated by extended spectrum beta lactamase (ESβL) and AmpC βL enzymes is an increasing problem worldwide. Presence of these in clinical infections can result in treatment failure if one of the second or third generation cephalosporins is used. Therefore, it is recommended that any ESβL-producing organism according to the National Committee for Clinical Laboratory Standards (NCCLS) criteria can be reported as resistant to all extended spectrum β lactam antibiotics regardless of the susceptibility test results. In this study, a total of 250 Escherichia coli (E. coli) isolates were subjected to Double disc test and AmpC disc test for the detection of ESβL- and AmpC βL-producing strains, respectively. Prevalence of ESβL- and AmpC βL-producing strains among E. coli isolates, over a 3-month-period in the hospital-based population of Jaipur, was 64.80% (162/250). AmpC βL producers were 24.00% (60/250) and co-existence of ESβL and AmpC βL was detected in 8.00% (20/250) of the isolates.


How to cite this article:
Sinha P, Sharma R, Rishi S, Sharma R, Sood S, Pathak D. Prevalence of extended spectrum beta lactamase and AmpC beta lactamase producers among Escherichia coli isolates in a tertiary care hospital in Jaipur.Indian J Pathol Microbiol 2008;51:367-369


How to cite this URL:
Sinha P, Sharma R, Rishi S, Sharma R, Sood S, Pathak D. Prevalence of extended spectrum beta lactamase and AmpC beta lactamase producers among Escherichia coli isolates in a tertiary care hospital in Jaipur. Indian J Pathol Microbiol [serial online] 2008 [cited 2021 Nov 27 ];51:367-369
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2008;volume=51;issue=3;spage=367;epage=369;aulast=Sinha;type=0