Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2009  |  Volume : 52  |  Issue : 1  |  Page : 110--112

Hemoglobin E disorders in Eastern Uttar Pradesh


Shashikant C.U Patne, Jyoti Shukla 
 Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi - 221005, Uttar Pradesh, India

Correspondence Address:
Jyoti Shukla
Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, Uttar Pradesh
India

The distribution of hemoglobin E (α2β2 26GluŽLys ) is mostly restricted to Northeastern India. While evaluating the patients of jaundice, we came across two cases of hemoglobin E (Hb E) disorders. The first case is in a 22-year-old Bengali male and the second case of Hb E/β thalassemia in a 5-year-old Hindu boy. The family study revealed Hb E trait in both the parents of Case 1, whereas in Case 2, the father was found to have Hb E trait and the mother had β -thalassemia minor, thus confirming the diagnosis. Herein, we present the laboratory diagnosis and comparative data of the spectrum of Hb E disorders (i.e., heterozygous Hb E trait, homozygous Hb E disease and compound heterozygous Hb E/β -thalassemia) that was found in our index cases and their parents.


How to cite this article:
Patne SC, Shukla J. Hemoglobin E disorders in Eastern Uttar Pradesh.Indian J Pathol Microbiol 2009;52:110-112


How to cite this URL:
Patne SC, Shukla J. Hemoglobin E disorders in Eastern Uttar Pradesh. Indian J Pathol Microbiol [serial online] 2009 [cited 2022 Jan 20 ];52:110-112
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=110;epage=112;aulast=Patne;type=0