Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2009  |  Volume : 52  |  Issue : 4  |  Page : 561--563

Transfusion related acute lung injury


Ratti Ram Sharma, Prasun Bhattacharya, Beenu Thakral, Karan Saluja, Neelam Marwaha 
 Department of Transfusion Medicine, PGIMER, Chandigarh, India

Correspondence Address:
Neelam Marwaha
Department of Transfusion Medicine, PGIMER, Chandigarh - 160 012
India

Transfusion related acute lung injury (TRALI) is an uncommon but potentially fatal adverse reaction to transfusion of plasma containing blood components. We describe a case of 10-year-old male child with aplastic anemia, platelet count of 7800/΅l, B positive blood group who developed fever (39.2΀C), difficulty in breathing and cyanosis within 2 hrs after transfusion of a random platelet concentrate. Despite the best resuscitative efforts, the child died within next 24 hrs. The present case highlights the fact that TRALI should be kept as a differential diagnosis in all patients developing acute respiratory discomfort within 6 hrs of transfusion. Without a «SQ»gold standard«SQ» the diagnosis of TRALI relies on a high index of suspicion and on excluding other types of transfusion reactions. Notification to transfusion services is crucial to ensure that a proper investigation is carried out and at-risk donor and recipients can be identified, and risk reduction measures can be adopted.


How to cite this article:
Sharma RR, Bhattacharya P, Thakral B, Saluja K, Marwaha N. Transfusion related acute lung injury.Indian J Pathol Microbiol 2009;52:561-563


How to cite this URL:
Sharma RR, Bhattacharya P, Thakral B, Saluja K, Marwaha N. Transfusion related acute lung injury. Indian J Pathol Microbiol [serial online] 2009 [cited 2021 Nov 27 ];52:561-563
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=4;spage=561;epage=563;aulast=Sharma;type=0