Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2012  |  Volume : 55  |  Issue : 4  |  Page : 509--512

Ovarian hemangioma with stromal luteinization and HCG-producing mononucleate and multinucleate cells of uncertain histogenesis: A rare co-existence with therapeutic dilemma


Murthy S Anand1, Shakila Shetty2, Vijaya V Mysorekar1, Rekha V Kumar3 
1 Department of Pathology, M.S. Ramaiah Medical College, Bangalore, India
2 Department of Obstetrics and Gynecology, M.S. Ramaiah Medical College, Bangalore, India
3 Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India

Correspondence Address:
Vijaya V Mysorekar
Department of Pathology, M.S.Ramaiah Medical College, Bangalore - 560 054
India

A 21 year old female presented with amenorrhea, hirsutism and change in voice along with an elevated serum β-HCG (human chorionic gonadotrophin) level and normal CA-125 level. Laparotomy revealed an enlarged right ovary measuring 6 × 5 × 1 cms with presence of an ovarian hemangioma along with stromal luteinization and HCG producing mononucleate as well as multinucleate cells of uncertain histogenesis on histopathological examination. Immunohistochemistry for inhibin and calretinin were positive in the luteinized component whereas β-HCG and Ki-67 were positive in the multinucleate cell component. The diagnostic rarity and therapeutic dilemma of such a rare mixed tumor within a single ovary has proven to be an exceptional case and an excellent investigative opportunity.


How to cite this article:
Anand MS, Shetty S, Mysorekar VV, Kumar RV. Ovarian hemangioma with stromal luteinization and HCG-producing mononucleate and multinucleate cells of uncertain histogenesis: A rare co-existence with therapeutic dilemma.Indian J Pathol Microbiol 2012;55:509-512


How to cite this URL:
Anand MS, Shetty S, Mysorekar VV, Kumar RV. Ovarian hemangioma with stromal luteinization and HCG-producing mononucleate and multinucleate cells of uncertain histogenesis: A rare co-existence with therapeutic dilemma. Indian J Pathol Microbiol [serial online] 2012 [cited 2020 Oct 21 ];55:509-512
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=4;spage=509;epage=512;aulast=Anand;type=0