Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2017  |  Volume : 60  |  Issue : 4  |  Page : 593--595

Fibroblast growth factor receptor-1 associated myeloproliferative neoplasm and T-lymphoblastic lymphoma


Gayathri Gopan1, TM Anoop1, NP Prakash1, Rakul Nambiar1, R Krishnachandran2 
1 Department of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India
2 Department of Cancer Research, Regional Cancer Centre, Thiruvananthapuram, Kerala, India

Correspondence Address:
Rakul Nambiar
Department of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala
India

Myeloid and lymphoid hematological malignancies with eosinophilia and abnormalities of fibroblast growth factor receptor-1 (FGFR1) result from the formation of abnormal fusion genes that encode constitutively activated tyrosine kinases. The WHO classification (2008) of hematolymphoid neoplasms recognizes a category of myeloid and lymphoid neoplasms with eosinophilia and abnormalities of FGFR1. Here, we present the case of a 30-year-old-woman who was diagnosed with T-lymphoblastic lymphoma from lymph node biopsy and myeloproliferative neoplasm with eosinophilia from bone marrow studies. She was treated with combination chemotherapy with cyclophosphamide, vincristine, doxorubicin, and dexamethasone (Hyper-CVAD regimen) and is on maintenance chemotherapy for the past 2 months. We present this case to create awareness among physicians about this rare condition associated with dual malignancies.


How to cite this article:
Gopan G, Anoop T M, Prakash N P, Nambiar R, Krishnachandran R. Fibroblast growth factor receptor-1 associated myeloproliferative neoplasm and T-lymphoblastic lymphoma.Indian J Pathol Microbiol 2017;60:593-595


How to cite this URL:
Gopan G, Anoop T M, Prakash N P, Nambiar R, Krishnachandran R. Fibroblast growth factor receptor-1 associated myeloproliferative neoplasm and T-lymphoblastic lymphoma. Indian J Pathol Microbiol [serial online] 2017 [cited 2021 Apr 20 ];60:593-595
Available from: https://www.ijpmonline.org/article.asp?issn=0377-4929;year=2017;volume=60;issue=4;spage=593;epage=595;aulast=Gopan;type=0