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  Indian J Med Microbiol
 

Figure 2: Si-PTEN promoted the proliferation, invasion, and migration of colon cancer cells. (a) qRT-PCR verified whether the PTEN was successfully knocked down. (b) MTT measured cell proliferation. (c) Flow cytometry measured cell cycle. (d) Western blot measured the expression of p38, p-p38, JNK, AP-1 in each group. (e) Expression of apoptosis-related proteins Bax, Bcl-2, and Caspase-3 in each group. (f) Transwell evaluated the migration and invasion of cancer cells. The data were expressed as mean ± standard deviation. The results were reproducible in three independent experiments. * P values < 0.05 vs. si-NC group

Figure 2: Si-PTEN promoted the proliferation, invasion, and migration of colon cancer cells. (a) qRT-PCR verified whether the PTEN was successfully knocked down. (b) MTT measured cell proliferation. (c) Flow cytometry measured cell cycle. (d) Western blot measured the expression of p38, p-p38, JNK, AP-1 in each group. (e) Expression of apoptosis-related proteins Bax, Bcl-2, and Caspase-3 in each group. (f) Transwell evaluated the migration and invasion of cancer cells. The data were expressed as mean ± standard deviation. The results were reproducible in three independent experiments. * <i>P</i> values < 0.05 <i>vs</i>. si-NC group