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Figure 5: Photomicrographs of an HER-2 gene amplifi ed case shown by IHC (a ×400; score 3+), FISH (b ×1000; amplifi cation seen by large gene clusters as represented by red clumps) and CISH (c ×400; amplifi cation seen by large gene clusters as represented by brown clumps within the nuclei) |
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