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  Indian J Med Microbiol
 

Figure 5: CagA+ Hp filtrate induced IL-8 secretion in a p38-dependent manner. (a) IL-8 secretion was analyzed in Ec 109 cells stimulated by Hp filtrates for 48 h in vitro; CagA+ Hp obviously stimulated IL-8 secretion. (b) Pretreatment with a p38 MAPK inhibitor for 1 h prior to treatment with Hp filtrates for 48 h inhibited IL-8 secretion. Error bars indicate the mean ± S.D. *P < 0.05 vs control, statistically significant

Figure 5: CagA+ Hp filtrate induced IL-8 secretion in a p38-dependent manner. (a) IL-8 secretion was analyzed in Ec 109 cells stimulated by Hp filtrates for 48 h in vitro; CagA+ Hp obviously stimulated IL-8 secretion. (b) Pretreatment with a p38 MAPK inhibitor for 1 h prior to treatment with Hp filtrates for 48 h inhibited IL-8 secretion. Error bars indicate the mean ± S.D. *P < 0.05 vs control, statistically significant