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  Indian J Med Microbiol
 

Figure 1: (a and b) Dense small lymphoid infiltrate admixed with few eosinophils and large atypical mononucleate and binucleate cells infiltrating the muscularispropria (H and E, ×100). Inset showing the submucosal granuloma formation (H and E, ×100). (c) Hodgkin and Reed–Sternberg cells (H and E, ×200). (d) Hodgkin and Reed–Sternberg cells admixed with several eosinophils (H and E, ×400). (e) Hodgkin and Reed–Sternberg cells are CD 30 positive (IHC, ×400) and inset showing the CD 20 negative Hodgkin and Reed–Sternberg cells (IHC, ×400). (f) PAX5 positive (IHC, ×400). (g) Epstein-Barr virus-encoded RNA positive (IHC, ×400)

Figure 1: (a and b) Dense small lymphoid infiltrate admixed with few eosinophils and large atypical mononucleate and binucleate cells infiltrating the muscularispropria (H and E, ×100). Inset showing the submucosal granuloma formation (H and E, ×100). (c) Hodgkin and Reed–Sternberg cells (H and E, ×200). (d) Hodgkin and Reed–Sternberg cells admixed with several eosinophils (H and E, ×400). (e) Hodgkin and Reed–Sternberg cells are CD 30 positive (IHC, ×400) and inset showing the CD 20 negative Hodgkin and Reed–Sternberg cells (IHC, ×400). (f) PAX5 positive (IHC, ×400). (g) Epstein-Barr virus-encoded RNA positive (IHC, ×400)