Figure 4: Whipple's disease (a) Per iodic acid-schiff, macrophages showing intense eosinophilic PAS-positive granular cytoplasm. (×400). (b) PAS with diastase, macrophages showing positivity for PAS with diastase (×400). (c) Ziehl-Neelsen stain, showing absence of acid-fast bacilli (×400)